Nigel Clough makes eight changes to the side that faced Sutton United on Saturday.
John-Joe O'Toole is not included in tonight's squad to face Manchester City U21 at One Call Stadium due to a foot injury.
Oli Hawkins misses out due to illness.
Scott Flinders, Kellan Gordon, Elliott Hewitt, Kieran Wallace, Ollie Clarke, George Maris, Jordan Bowery and James Gale all come into the Stags' starting XI.
Christy Pym, James Perch, Anthony Hartigan, Stephen Quinn, George Lapslie and Will Swan join Hawkins and O'Toole in making way.
Ollie Clarke captains Mansfield this evening.
Starting XI: Flinders, Gordon, Hewitt, Harbottle, McLaughlin, Clarke, Wallace, Maris, Akins, Gale, Bowery.
Subs: Pym, Perch, Hartigan, Quinn, Lapslie, Boateng, Swan.
