Nigel Clough makes three changes to the side that faced Derby County in the Carabao Cup first round on Tuesday.
Rhys Oates, Hiram Boateng and Riley Harbottle come into the XI for this afternoon's encounter at Leyton Orient.
Jordan Bowery (suspended), George Lapslie and Oli Hawkins make way.
Stephen McLaughlin captains Mansfield at Brisbane Road.
Kellan Gordon makes his first league start for 11 months.
Starting XI: Pym, Gordon, O'Toole, Harbottle, Hewitt, McLaughlin ©, Boateng, Hartigan, Quinn, Oates, Swan.
Subs: Flinders, Perch, Wallace, Clarke, Maris, Lapslie, Gale.