Stags' under-18s will travel to face Bournemouth under-18s at the Vitality Stadium on Wednesday 12 December in the third round of the FA Youth Cup (7pm kick-off).
Mansfield progressed to the third round of the competition after wins over Grimsby Town at Blundell Park, and Chester at One Call Stadium.
John Dempster's side came back from 2-0 down away to the Mariners to record a stunning second half comeback, earning their progression to the next stage of the competition. The goals came from Tyrese Sinclair, Rhys Sarson and Riley O'Sullivan in the 3-2 victory.
In the second round, Mansfield welcomed Chester to One Call Stadium, and recorded a convincing 2-0 win, with goals coming from forwards Jimmy Knowles and O'Sullivan.
Wednesday's fixture will be the first FA Youth Cup clash of the Cherries' season, with Premier League and Championship clubs entering the competition at the third round.
Bournemouth under-18s currently sit in second place of the EFL Youth Alliance Southwest Division, and have found the net an impressive 44 times in 16 league matches.
Stags also sit second in their league, two points behind leaders Grimsby.
Should the Stags make it to the fourth round of the competition, they will face either Burnley or Oxford United away from home.
The venue for Wednesday evening's game is as follows: Vitality Stadium, Kings Park Avenue, BH7 7AF.
Admission prices for the match are:
Under-21s & Over-65s: £3
Wheelchair disabled: £1 (Carer free of charge)